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the Anglo Platinum Bubble Sizer (APBS) developed by Stone Three Technology, which measures bubbles on industrial flotation cells, was used. The APBS works by maintaining an unbroken column of water from deep within the flotation cell where the bubbles
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· We talk to Prashant Rawat and Marc Boehning, collaborators and co-first authors of "Stress-induced nuclear condensation of NELF drives global transcriptional downregulation" (this issue, previewed by Xu et al.), about their motivation for becoming scientists, the challenges they faced in the course of their project, and the importance of collaboration for scientific research.
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Glutaminolysis and Transferrin Regulate Ferroptosis
We further found that the cell surface transferrin receptor and the glutamine-fueled intracellular metabolic pathway, glutaminolysis, played crucial roles in the death process. Inhibition of glutaminolysis, the essential component of ferroptosis, can reduce heart injury triggered by ischemia/reperfusion, suggesting a potential therapeutic approach for treating related diseases.
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